1/27/2024 0 Comments Sequencher 3.1![]() Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3. Mapping of primary congenital lymphedema to the 5q35.3 region. Phenotypic and genotypic heterogeneity in familial Milroy lymphedema. ![]() Hereditary lymphedema: evidence for linkage and genetic heterogeneity. in Vascular Pathology (eds Stehbens, W.E. Diseases of the veins and lymphatic vessels, including angiodysplasias. An undescribed variety of hereditary oedema. VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggest a role in lymphatic vascular development. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Expression of the fms-like tyrosine kinase FLT4 gene becomes restricted to endothelium of lymphatic vessels during development. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor. FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines. Regulation of angiogenesis via vascular endothelial growth factor receptors. Veikkola, T., Karkkainen, M.J., Claesson-Welsh, L. Molecular and biological properties of vascular endothelial growth factor. Signaling angiogenesis and lymphangiogenesis.
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